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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > kinase > Tocris/AG 18/0493/10/10 mg
商品详细Tocris/AG 18/0493/10/10 mg
Tocris/AG 18/0493/10/10 mg
Tocris/AG 18/0493/10/10 mg
商品编号: 0493/10
品牌: Tocris Bioscience
市场价: ¥2500.00
美元价: 1500.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:EGFR/PDGFR-kinaseinhibitor
AlternativeNames:RG-50810,TyrphostinA23
ChemicalName:[(3,4-Dihydroxyphenyl)methylene]-propenedinitrile
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofepidermalgrowthfactorreceptor(EGFR)andplatelet-derivedgrowthfactorreceptor(PDGFR)kinase(IC50valuesare35and25μMrespectively).InhibitsEGF-stimulatedcellproliferation.Alsoactsasamitochondrialuncouplerthataltersphosphorylation-dependentcellsignaling.

TechnicalData

M.Wt186.17
FormulaC10H6N2O2
StorageDesiccateat+4°C
CASNumber118409-57-7
PubChemID2052
InChIKeyVTJXFTPMFYAJJU-UHFFFAOYSA-N
SmilesOC1=C(O)C=C(C=C(/C#N)C#N)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.62100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight186.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.37mL26.86mL53.71mL
5mM1.07mL5.37mL10.74mL
10mM0.54mL2.69mL5.37mL
50mM0.11mL0.54mL1.07mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet