Tocris/AG 494/0619/10/10 mg
商品编号：
0619/10
市场价：
¥2500.00
美元价：
1500.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentEGFR-kinaseinhibitor
ChemicalName:(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentinhibitorofepidermalgrowthfactorreceptor(EGFR)kinase(IC50=0.7μM).SelectiveoverErbB2,PDGFRandinsulinreceptorkinase(IC50valuesare42,6and>100μMrespectively).
TechnicalData
| M.Wt | 280.28 |
| Formula | C16H12N2O3 |
| Storage | Desiccateat+4°C |
| CASNumber | 133550-35-3 |
| PubChemID | 5328771 |
| InChIKey | HKHOVJYOELRGMV-XYOKQWHBSA-N |
| Smiles | OC1=C(O)C=C(C=C(/C#N)C(=O)NC2=CC=CC=C2)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 14.01 | 50 | |
| ethanol | 1.4 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight280.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.57mL | 17.84mL | 35.68mL |
| 5mM | 0.71mL | 3.57mL | 7.14mL |
| 10mM | 0.36mL | 1.78mL | 3.57mL |
| 50mM | 0.07mL | 0.36mL | 0.71mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet