4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > kinase > Tocris/AG 555/0618/50/50毫克
商品详细Tocris/AG 555/0618/50/50毫克
Tocris/AG 555/0618/50/50毫克
Tocris/AG 555/0618/50/50毫克
商品编号: 0618/50
品牌: Tocris Bioscience
市场价: ¥10700.00
美元价: 6420.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentEGFR-kinaseinhibitor
AlternativeNames:TyrphostinAG555
ChemicalName:(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentepidermalgrowthfactorreceptor(EGFR)kinaseinhibitor(IC50=0.7μM)thatdisplays50-foldand>140-foldselectivityoverErbB2andinsulinreceptorkinaserespectively.InduceG1growtharrestselectivelyintransformedcells(IC50valuesare6.4and9.4μMinHPV16-immortalizedandnormalkeratinocytesrespectively).

TechnicalData

M.Wt322.36
FormulaC19H18N2O3
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber133550-34-2
PubChemID5328770
InChIKeyGSQOBTOAOGXIFL-LFIBNONCSA-N
SmilesOC1=CC=C(C=C(/C#N)C(=O)NCCCC2=CC=CC=C2)C=C1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.6730

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight322.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.1mL15.51mL31.02mL
5mM0.62mL3.1mL6.2mL
10mM0.31mL1.55mL3.1mL
50mM0.06mL0.31mL0.62mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet