Tocris/AG 99/0497/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AG 99/0497/50/50 mg

Tocris/AG 99/0497/50/50 mg

商品编号： 0497/50

品牌： Tocris Bioscience

市场价： ¥10500.00

美元价： 6300.00

产地：美国(厂家直采)

公司：

产品分类：激酶

公司分类： kinase

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:EGFR-kinaseinhibitor

ChemicalName:(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Epidermalgrowthfactorreceptor(EGFR)kinaseinhibitor(IC₅₀=10μM)thatisselectiveoverinsulinreceptorkinase.Blockstyrosinephosphorylationofp145^metandpromotescelldeathofnormalandcancercellsviaactivationofcaspase-likeproteasesinvitro.

TechnicalData

M.Wt	204.18
Formula	C₁₀H₈N₂O₃
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	122520-85-8
PubChemID	5328768
InChIKey	USOXQZNJFMKTKJ-XVNBXDOJSA-N
Smiles	NC(=O)C(=CC1=CC(O)=C(O)C=C1)C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	20.42	100
	ethanol	1.02	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight204.18.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	4.9mL	24.49mL	48.98mL
5mM	0.98mL	4.9mL	9.8mL
10mM	0.49mL	2.45mL	4.9mL
50mM	0.1mL	0.49mL	0.98mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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