Tocris/AK 7/4754/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AK 7/4754/50/50 mg

Tocris/AK 7/4754/50/50 mg

商品编号： 4754/50

品牌： Tocris Bioscience

市场价： ¥11700.00

美元价： 7020.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveSIRT2inhibitor;brainpenetrant

ChemicalName:N-(3-Bromophenyl)-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveSIRT2inhibitor(IC₅₀=15.5μM);displaysnoeffectonSIRT1orSIRT3.Decreasesneuronalcholesterollevels;improvesmotorfunctionandamelioratesbrainatrophyinamousemodelofHuntington'sdisease.Brainpenetrant.

CompoundLibraries

AK7isalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	437.35
Formula	C₁₉H₂₁BrN₂O₃S
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	420831-40-9
PubChemID	1328033
InChIKey	IYAYHZZWYNXHEQ-UHFFFAOYSA-N
Smiles	O=C(NC2=CC(Br)=CC=C2)C1=CC(S(N3CCCCCC3)(=O)=O)=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.73	100
	ethanol	4.37	10mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight437.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.29mL	11.43mL	22.86mL
5mM	0.46mL	2.29mL	4.57mL
10mM	0.23mL	1.14mL	2.29mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets