Tocris/AL 8697/4753/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AL 8697/4753/10/10 mg

Tocris/AL 8697/4753/10/10 mg

商品编号： 4753/10

品牌： Tocris Bioscience

市场价： ¥4900.00

美元价： 2940.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentandselectivep38αinhibitor

ChemicalName:N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivep38αinhibitor(IC₅₀=6nM).Exhibits14-foldgreaterinhibitionofp38αcomparedtop38β;alsodisplays300-foldselectivityforp38αcomparedtoapanelof91kinases.Exhibitsanti-inflammatoryproperties.

CompoundLibraries

AL8697isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxII.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	402.41
Formula	C₂₁H₂₁F₃N₄O
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1057394-06-5
PubChemID	25060093
InChIKey	ZVBTZTQYHOXIBC-UHFFFAOYSA-N
Smiles	CC1=C(F)C=C(C(NC4CC4)=O)C=C1C3=C(F)C2=NN=C(C(C)(C)C)N2C=C3F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.24	100
	ethanol	20.12	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight402.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.49mL	12.43mL	24.85mL
5mM	0.5mL	2.49mL	4.97mL
10mM	0.25mL	1.24mL	2.49mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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