Tocris/AM 114/2564/50/50毫克
商品编号：
2564/50
市场价：
¥11700.00
美元价：
7020.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:20Sproteasomeinhibitor
ChemicalName:3,5-Bis-[benzylidene-4-boronicacid]-1-methylpiperidin-4-one
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inhibitorofthechymotrypsin-likeactivityofthe20Sproteasome(IC50~1μM).Displaysanticanceractivity;inhibitscellgrowthinhumancoloncancerHCT116p53+/+cells(IC50=1.49μM).
LicensingInformation
SoldwiththepermissionofJohnsHopkinsUniversity
TechnicalData
| M.Wt | 377.01 |
| Formula | C20H21B2NO5 |
| Storage | Storeat+4°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 856849-35-9 |
| PubChemID | 11639443 |
| InChIKey | SRPIKXGUPAKTIZ-OTYYAQKOSA-N |
| Smiles | O=C(/C(CN(C)C3)=C/C2=CC=C(B(O)O)C=C2)/C3=C/C1=CC=C(B(O)O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 3.77 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight377.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.65mL | 13.26mL | 26.52mL |
| 5mM | 0.53mL | 2.65mL | 5.3mL |
| 10mM | 0.27mL | 1.33mL | 2.65mL |
| 50mM | 0.05mL | 0.27mL | 0.53mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet