Tocris/AMG 517/5995/50/50毫克
商品编号：
5995/50
市场价：
¥14300.00
美元价：
8580.00
产品分类：
信号通路
公司分类：
Signal_pathway
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:PotentTRPV1antagoNIST
ChemicalName:N-[4-[[6-[4-(Trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentTRPV1antagonist(IC50=0.9nM).Inhibitscapsaican-inducedflinchingandreversesanalgesiainaninflammatorypainmodelinrats.Orallybioavailable.
TechnicalData
| M.Wt | 430.41 |
| Formula | C20H13F3N4O2S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 659730-32-2 |
| PubChemID | 16007367 |
| InChIKey | YUTIXVXZQIQWGY-UHFFFAOYSA-N |
| Smiles | O=C(NC(S1)=NC(C1=CC=C2)=C2OC3=NC=NC(C4=CC=C(C(F)(F)F)C=C4)=C3)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 43.04 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight430.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.32mL | 11.62mL | 23.23mL |
| 5mM | 0.46mL | 2.32mL | 4.65mL |
| 10mM | 0.23mL | 1.16mL | 2.32mL |
| 50mM | 0.05mL | 0.23mL | 0.46mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet