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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/AMG 9810/2316/10/10 mg
商品详细Tocris/AMG 9810/2316/10/10 mg
Tocris/AMG 9810/2316/10/10 mg
Tocris/AMG 9810/2316/10/10 mg
商品编号: 2316/10
品牌: Tocris Bioscience
市场价: ¥3500.00
美元价: 2100.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentandselective,competitiveantagoNISTofTRPV1
ChemicalName:(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselective,competitivevanilloidTRPV1receptorantagonist(IC50=17nM).Inhibitscapsaicin-,proton-,heat-andendogenousligand-inducedactivationofhumanandratrecombinantTRPV1receptors.Displaysantihyperalgesicpropertiesinaratmodelofinflammatorypain.

CompoundLibraries

AMG9810isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt337.42
FormulaC21H23NO3
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber545395-94-6
PubChemID680502
InChIKeyGZTFUVZVLYUPRG-IZZDOVSWSA-N
SmilesCC(C)(C)C1=CC=C(C=C1)C=CC(=O)NC1=CC=C2OCCOC2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO16.8750
ethanol33.74100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight337.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.96mL14.82mL29.64mL
5mM0.59mL2.96mL5.93mL
10mM0.3mL1.48mL2.96mL
50mM0.06mL0.3mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet