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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/GW 5074/1381/10/10 mg
商品详细Tocris/GW 5074/1381/10/10 mg
Tocris/GW 5074/1381/10/10 mg
Tocris/GW 5074/1381/10/10 mg
商品编号: 1381/10
品牌: Tocris Bioscience
市场价: ¥3380.00
美元价: 2028.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potent,selectivec-Raf1kinaseinhibitor
ChemicalName:3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveandcell-permeablec-Raf1kinaseinhibitor(IC50=9nM).Displays≥100-foldselectivityforrafkinaseoverCDK1,CDK2,c-src,ERK2,MEK,p38,Tie2,VEGFR2andc-fm.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoWellcomeIncandGlaxoGroupLtd.

TechnicalData

M.Wt520.94
FormulaC15H8Br2INO2
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber220904-83-6
PubChemID5924208
InChIKeyLMXYVLFTZRPNRV-KMKOMSMNSA-N
SmilesOC1=C(Br)C=C(C=C2/C(=O)NC3=CC=C(I)C=C23)C=C1Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mMinethanolandto100mMinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight520.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.92mL9.6mL19.2mL
5mM0.38mL1.92mL3.84mL
10mM0.19mL0.96mL1.92mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet