Biological Activity
Selective agonist for 'quis'-sensitized site.
Technical Data
| M. Wt | 211.15 |
| Formula | C6H14NO5P |
| Storage | Store at RT |
| CAS Number | 78944-89-5 |
| PubChem ID | 3062646 |
| InChI Key | QIOXWRQXHFVNLV-YFKPBYRVSA-N |
| Smiles | [H][C@@](CCCCP(O)(O)=O)(N)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in 1eq. NaOH |
Preparing Stock Solutions
The following data is based on the product molecular weight 211.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.74 mL | 23.68 mL | 47.36 mL |
| 5 mM | 0.95 mL | 4.74 mL | 9.47 mL |
| 10 mM | 0.47 mL | 2.37 mL | 4.74 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.95 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Johansen et al (1995) Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats. Mol.Pharmacol. 48 140 PMID: 7623768
Schulte et al (1994) Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons. Brain Res. 649 203 PMID: 7953634
Venkatraman et al (1994) Synthesis of oxadiazolidinedione derivatives as quisqualic acid analogues and their evaluation at a quisqualate-sensitized site in the rat hippocampus. J.Med.Chem. 37 3939 PMID: 7966155
Keywords: L-AP6, supplier, Selective, agonists, quis, effect, Glutamate, mGlur, Receptors, Metabotropic, iGluR, Ionotropic, Miscellaneous, Glutamate, Miscellaneous, Glutamate, Tocris Bioscience
