Biological Activity
First generation phosphono NMDA antagonist. Anticonvulsant.
Technical Data
| M. Wt | 225.18 |
| Formula | C7H16NO5P |
| Storage | Store at RT |
| CAS Number | 78966-69-5 |
| PubChem ID | 3122 |
| InChI Key | MYDMWESTDPJANS-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)CCCCCP(O)(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in 1eq. NaOH |
Preparing Stock Solutions
The following data is based on the product molecular weight 225.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.44 mL | 22.2 mL | 44.41 mL |
| 5 mM | 0.89 mL | 4.44 mL | 8.88 mL |
| 10 mM | 0.44 mL | 2.22 mL | 4.44 mL |
| 50 mM | 0.09 mL | 0.44 mL | 0.89 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024
Meldrum and Chapman (1994) Competitive NMDA antagonists as drugs. In The NMDA Receptor (2nd edition). Eds. G. L. Col 457 PMID:
Keywords: DL-AP7, supplier, Selective, Specific, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGlu, Ionotropic, NMDA, Receptors, NMDA, Receptors, Tocris Bioscience
