Tocris/AR-C 102222/3969/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AR-C 102222/3969/10/10毫克

Tocris/AR-C 102222/3969/10/10毫克

商品编号： 3969/10

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveiNOSinhibitor

ChemicalName:5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrilehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InducIBLenitricoxidesynthase(iNOS)inhibitor;selectiveforiNOSovereNOS(IC₅₀valuesare0.037and>100μMforiNOSandeNOSrespectively).Exhibitsantinociceptiveandanti-inflammatoryactivityinrodentpainmodels.

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

TechnicalData

M.Wt	418.83
Formula	C₁₉H₁₆F₂N₆O.HCl
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	253771-21-0
PubChemID	21192822
InChIKey	FJFMOBYDHGJDGV-UHFFFAOYSA-N
Smiles	O=C(C4=CC=C(C#N)N=C4)N(CC3)CCC23N=C(N)C1=C(F)C=CC(F)=C1N2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.86	100
	water	10.47	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.39mL	11.94mL	23.88mL
5mM	0.48mL	2.39mL	4.78mL
10mM	0.24mL	1.19mL	2.39mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets