Tocris/ARL 17477二盐酸盐/3319/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ARL 17477二盐酸盐/3319/50/50 mg

Tocris/ARL 17477二盐酸盐/3319/50/50 mg

商品编号： 3319/50

品牌： Tocris Bioscience

市场价： ¥11700.00

美元价： 7020.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectivenNOSinhibitor

ChemicalName:N-[4-[2-[[(3-Chlorophenyl)methyl]amino]ethyl]phenyl]-2-thiophenecarboxamidedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveneuronalnitrogenoxidesynthase(nNOS)inhibitor(IC₅₀valuesare1and17μMfornNOSandendothelialNOSrespectively).Reducesischemiccelldamageaftermiddlecerebralartery(MCA)occlusioninrats.DisplaysasynergisticneuroprotectiveeffectwhencombinedwitheitheranNMDAorAMPAreceptorantagoNIST.

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

TechnicalData

M.Wt	442.83
Formula	C₂₀H₂₀ClN₃S.2HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	866914-87-6
PubChemID	9824646
InChIKey	SOXBYIKSUDXMIE-UHFFFAOYSA-N
Smiles	ClC1=CC=CC(CNCCC2=CC=C(NC(C3=CC=CS3)=N)C=C2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	44.28	100
	water	22.14	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight442.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.26mL	11.29mL	22.58mL
5mM	0.45mL	2.26mL	4.52mL
10mM	0.23mL	1.13mL	2.26mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets