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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/AS 605240/3578/10/10 mg
商品详细Tocris/AS 605240/3578/10/10 mg
Tocris/AS 605240/3578/10/10 mg
Tocris/AS 605240/3578/10/10 mg
商品编号: 3578/10
品牌: Tocris Bioscience
市场价: ¥3100.00
美元价: 1860.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectivePI3-kinaseγ(PI3-Kγ)inhibitor
ChemicalName:5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitorofPI3-kinaseγ(PI3-Kγ)(IC50=8nM).Displays30-foldselectivityoverPI3-KδandPI3-Kβand7.5-foldselectivityoverPI3-Kα.Suppressestheprogressionofjointinflammationanddamageinbothlymphocyte-independentandlymphocyte-dependentmousemodelsofrheumatoidarthritis.OrallyactiveandATP-competitive.

TechnicalData

M.Wt257.27
FormulaC12H7N3O2S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber648450-29-7
PubChemID5289247
InChIKeySQWZFLMPDUSYGV-POHAHGRESA-N
SmilesO=C(/C(S3)=C/C(C=C2)=CC1=C2N=CC=N1)NC3=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO0.261mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight257.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.89mL19.43mL38.87mL
5mM0.78mL3.89mL7.77mL
10mM0.39mL1.94mL3.89mL
50mM0.08mL0.39mL0.78mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet