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当前位置: 首页 > 产品中心 > Transporters > Tocris/ASP 2535/5308/10/10 mg
商品详细Tocris/ASP 2535/5308/10/10 mg
Tocris/ASP 2535/5308/10/10 mg
Tocris/ASP 2535/5308/10/10 mg
商品编号: 5308/10
品牌: Tocris Bioscience
市场价: ¥4700.00
美元价: 2820.00
产地: 美国(厂家直采)
公司:
产品分类: 转运体
公司分类: Transporters
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentandselectiveGlyT1inhibitor
ChemicalName:4-[3-(1-Methylethyl)-5-(6-phenyl-3-pyridinyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxADIazole
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGlyT1inhibitor(IC50=92nM).Exhibits50-foldselectivityoverGlyT2.AttenuatesMK801-inducedworkingmemorydeficitsandPCP-inducedvisuallearningdeficitsinmice.Orallyavailableandbrainpenetrant.

CompoundLibraries

ASP2535isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt382.42
FormulaC22H18N6O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber374886-51-8
PubChemID9800113
InChIKeyFQGLDGKVKDPVLO-UHFFFAOYSA-N
SmilesCC(C)C1=NN=C(C4=CN=C(C5=CC=CC=C5)C=C4)N1C3=CC=CC2=NON=C23

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.24100
ethanol38.24100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight382.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.61mL13.07mL26.15mL
5mM0.52mL2.61mL5.23mL
10mM0.26mL1.31mL2.61mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet