Tocris/AZD 3147/5615/10/10毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/AZD 3147/5615/10/10毫克

Tocris/AZD 3147/5615/10/10毫克

商品编号： 5615/10

品牌： Tocris Bioscience

市场价： ¥4780.00

美元价： 2868.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectivedualmTORC1and2inhibitor;orallybioavailable

ChemicalName:N-[4-[4-[1-(Cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)thiourea

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivedualmTORC1and2inhibitor(IC₅₀=1.5nM).Exhibits>300-foldselectivityformTORoverPI3-kinaseisoforms.Orallybioavailable.

CompoundLibraries

AZD3147isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	517.66
Formula	C₂₄H₃₁N₅O₄S₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1101810-02-9
PubChemID	25168990
InChIKey	JWGVUDPAMQEIJU-INIZCTEOSA-N
Smiles	OCCNC(NC(C=C1)=CC=C1C2=NC(C3(CC3)S(C4CC4)(=O)=O)=CC(N5[C@@H](C)COCC5)=N2)=S

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	51.77	100
	DMSO	51.77	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight517.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.93mL	9.66mL	19.32mL
5mM	0.39mL	1.93mL	3.86mL
10mM	0.19mL	0.97mL	1.93mL
50mM	0.04mL	0.19mL	0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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