我们如何帮助您？
关闭开始聊天技术支持获得技术支持再简单不过了。以下链接包含对技术支持提出的最常见问题的解答 - 单击任何链接以获取更多信息。
目录条目信息半衰期化合物文库分子量SDS 和 CoAPeptides 准备溶液作为摩尔当量准备储备溶液产品外观纯度安全溶解度稳定性和储存无菌运输期间的温度运输分类小瓶标签如果您没有找到所需的答案，请填写技术咨询表。或者，请联系我们以获取更多信息和帮助。Tocris 是 Bio-Techne 的品牌。要了解更多信息，请访问我们的新闻页面。
客户支持提供卓越的客户支持获得客户支持再简单不过了。以下链接包含客户支持最常见问题的答案 - 单击任何链接以获取更多信息。
散装数量受控物质货币设置危险品新产品建议和许可新产品更新订购信息隐私和 Cookie 政策产品可用性退货政策运输时间和费用条款和条件of SaleToxinsValue Added Tax我们如何帮助您？
关闭开始聊天如果找不到答案，请填写客户咨询表你正在寻找。或者，请联系我们以获取更多信息和帮助。Tocris 是 Bio-Techne 的品牌。要了解更多信息，请访问我们的新闻页面。
支持在这里提供卓越的服务和支持大批量联系我们客户支持分销商 GMP 复合查询留下反馈促销筛选查询提交评论技术支持 Tocris 奖学金计划研究领域研究领域是根据其特征性的主要疾病进行分类的。使用下面的链接查找对研究这些研究领域和疾病有用的产品和支持服务。
研究领域癌症研究心血管系统研究细胞和基因治疗研究COVID-19 研究内分泌学研究免疫学研究传染病研究神经科学研究疼痛和炎症研究呼吸系统研究特色新产品7645 | FHT 2344强效 SMARCA2/4 抑制剂7892 |用于标记突变体 FKBP12F36V 蛋白的 dTAG-荧光素荧光探针7368 | Cell Counting Kit-8细胞活力及增殖检测试液7842 | NAMPT PROTAC® A7强效选择性烟酰胺磷酸核糖转移酶降解剂7898 | ZZL 7 SERT 和 nNOS 之间相互作用的抑制剂我们如何帮助您？
关闭开始聊天Description: Peripheral H1 antagonist; antiallergic agent Alternative Names: SCH 29851 Chemical Name: 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester Purity: ≥99% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferencesBiological Activity
Peripheral histamine H1 receptor antagonist (Ki = 35 nM); devoid of central effects. Orally active antiallergic agent.
Compound Libraries
Loratidine is also offered as part of the Tocriscreen Plus and Tocriscreen Library of FDA-Approved Compounds. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 382.88 |
| Formula | C22H23ClN2O2 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 79794-75-5 |
| PubChem ID | 3957 |
| InChI Key | JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| Smiles | CCOC(=O)N1CCC(CC1)=C1/C2=NC=CC=C2CCC2=C1C=CC(Cl)=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| DMSO | 9.57 | 25 |
| ethanol | 38.29 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 382.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 1 mM | 2.61 mL | 13.06 mL | 26.12 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.61 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.52 mL |
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution. Reconstitution CalculatorReconstitution Calculator
Dilution CalculatorDilution Calculator
Calculate the dilution required to prepare a stock solution.Product Datasheets
Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDSReferences
References are publications that support the products\' biological activity.
Ahn and Barnett (1986) Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine. Eur.J.Pharmacol. 127 153 PMID: 2875889
Barnett et al (1984) Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions 14 590 PMID: 6236679
Kreutner et al (1987) Antiallergic activity of loratidine, a non-sedating antihistamine. Allergy 42 57 PMID: 2436504
Keywords: Loratidine, supplier, Peripheral, H1, antagonists, anti-allergic, agent, Receptors, Histamine, histaminergic, SCH29851, SCH, 29851, Histamine, H1, Receptors, Histamine, H1, Receptors, Tocris Bioscience
本文链接： http://tocris.immuno-online.com/view-1598414272.html
