Biological Activity
Endogenous hormone that acts as an agonist at melatonin receptors MT1 and MT2. Exhibits a prominent role in the control of circadian rhythm, displays immunomodulatory activity and acts as a powerful antioxidant in vivo.
Compound Libraries
Melatonin is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 232.28 |
| Formula | C13H16N2O2 |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 73-31-4 |
| PubChem ID | 896 |
| InChI Key | DRLFMBDRBRZALE-UHFFFAOYSA-N |
| Smiles | O=C(C)NCCC2=CNC1=CC=C(OC)C=C12 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| DMSO | 11.61 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 232.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 1 mM | 4.31 mL | 21.53 mL | 43.05 mL |
| 5 mM | 0.86 mL | 4.31 mL | 8.61 mL |
| 10 mM | 0.43 mL | 2.15 mL | 4.31 mL |
| 50 mM | 0.09 mL | 0.43 mL | 0.86 mL |
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Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDSReferences
References are publications that support the products\' biological activity.
Bubenik (2008) Thirty four years since the discovery of gastrointestinal melatonin. J.Physiol.Pharmacol. 59 33 PMID: 18812627
Fischer et al (2008) Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair. Exp.Dermatol. 17 713 PMID: 18643846
Cardinali et al (2009) Melatonin and melatonergic drugs on sleep: possible mechanisms of action. Int.J.Neurosci. 119 821 PMID: 19326288
Keywords: Melatonin, supplier, Endogenous, hormone, agonists, MT1, MT2, Receptors, Melatonin, circadian, rhythms, Melatonin, (MT), Receptors, Melatonin, (MT), Receptors, Tocris Bioscience
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